Website hosted in local iis not working

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ASP.NET

VS2010

ASP.NET4

i am using Visual studio web developer 4.0, in which i doing a web application. And i hosted my website in my local IIS. My problem is while i am opening the website from visual studio some alter message is coming like

ASP.NET 4.0 has not been registered on the webserver. You need to manually configure your web server for asp.net 4.0 in order for your site to run correctly...

An then when i am trying to debugg website bellow error i am getting

Unable to start debugging on the server. Could not start asp.net debugging. More information my available by starting the project without debugging.

Then i browsed my startup page without debugging then the error in browser is

The page you are requesting cannot be served because of the extension configuration. If the page is a script, add a handler. If the file should be downloaded, add a MIME map.

i tried many things like registering asp.net with aspnet_regiis -1, and searched a lot bt not working. and i m using windows 8.

Pls help.