Microsoft JScript runtime error: Sys.WebForms.PageRequestManagerTimeoutException: The server request timed out.

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The problem you are facing because of When your application runs into a timeout on a sql database query's. It taking more than default time to return out put. So you need to increase ConnectionTimeout property.

You can do it in several ways

1. A ConnectionString has a ConnectionTimeout property. It is a property which determines the maximum number of seconds your code will wait for a connection of the database to be open. You can set connection timeout in connection string section in web.config.

<connectionstrings>
      
<add name="ConnectionString" connectionstring="Database=UKTST1;Server=BRESAWN;uid=" system.data.sqlclient="/><br mode=" hold=" /><br mode=" html="> <asp:ToolkitScriptManager runat=" server=" AsyncPostBackTimeOut=" 6000="><br mode="></add></connectionstrings>

2. You can put AsyncPostBackTimeout="6000" in .aspx page

<asp:ToolkitScriptManager runat="server"; AsyncPostBackTimeOut="6000";
   </asp:ToolkitScriptManager>

3. You can set timeout in sqlcommand where you are calling storeprocedure in .cs file.

command.CommandTimeout = 30*1000;

hope you have got solution.