change connection setting aspx

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ASP.NET

CrystalReports

I have this code in index.aspx

<%@ Register assembly="CrystalDecisions.Web, Version=10.5.3700.0, Culture=neutral, PublicKeyToken=692fbea5521e1304" namespace="CrystalDecisions.Web" tagprefix="CR" %>
<%@ Page Language="VB" %>

<script runat="server">

    Sub Page_Load(sender As Object, e As EventArgs)

        Dim  myDataReport
        Dim  crtableLogoninfo
        Dim crConnectionInfo

        myDataReport = new CrystalDecisions.CrystalReports.Engine.ReportDocument()
        myDataReport.Load("C:\inetpub\wwwroot\agora\CrystalReport1.rpt")

        Me.CrystalReportViewer1.ReportSource = myDataReport

    End Sub

</script>

The connection string is in the RPT, is a OBDC mysql connection and all work fine, but i want change the database, server etc before call the rpt how can i do that? Also other question is possible to change the QUERY also?

Thanks a lot for your help