what is this error Ajax AsyncFileUpload?

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ASP.NET

Ajax

Hi,
I used this ajax control in my project and my Debugger get this error

"0x800a01bd - JavaScript runtime error: Object doesn't support this action"

this is my code:

<div class="FontFamily">
                                <div>
                                    <asp:Label runat="server" CssClass="fit">TEST</asp:Label>
                                    <div>
                                        <asp:TextBox runat="server" ID="TextBox1" CssClass="TextBox-control fit" />
                                        <%--<asp:RequiredFieldValidator runat="server" ControlToValidate="Email"
                                        CssClass="text-danger" ErrorMessage="The email field is required." />--%>
                                    </div>
                                </div>
                                <div>
                                    <div>
                                        <asp:Label runat="server" CssClass="fit">TEST</asp:Label>
                                        <div>
                                            <cc1:Editor ID="Editor1" runat="server" Width="650" Height="300" />
                                            <%--<asp:RequiredFieldValidator runat="server" ControlToValidate="Email"
                                            CssClass="text-danger" ErrorMessage="The email field is required." />--%>
                                        </div>
                                    </div>
                                </div>
                                <div dir="ltr">
                                    <asp:Label runat="server" CssClass="fit">TEST</asp:Label>
                                    <%--<asp:AsyncFileUpload ID="AsyncFileUpload1" runat="server"                                                                       CssClass="FontFamily" />--%>
                                    <asp:AsyncFileUpload ID="AsyncFileUpload1" runat="server" OnUploadedFileError="AsyncFileUpload1_UploadedFileError" />
                                </div>
                            </div>

Somethings is cool when try to upload pic in other project never get this error??????????

what is problem in this project??????????

just something you must know is this This div in side of Update panel and this update panel shown in ModalPopupExtender.

and used ToolkitScriptManager in master page.

plz help me THANKS.