The articles describes how to use and leverage MS CRM adapter to integrate CRM system with BizTalk.
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How to Integrate Microsoft Dynamics CRM 4.0 using BizTalk Server 2009/2010 to Other Business Applications
Monitoring BizTalk Server using BizTalk Control Center (BCC) for BizTalk Server 2006 R2 / 2009 / 2010
Dynamic Message Processing and Routing in Itineraries using BizTalk 2010 with Enterprise Service Bus Toolkit 2.1
Implementing a Leave Application Workflow System using BizTalk Server 2006 and Sharepoint Server 2003