save changes of dataGridView to database

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C#

DataGridView

I have from form with dataGridView1 and delete button
and I have this code for delete a row, how can make this delete saved to the database ?? I filled the dataGridView1 with dataset.

if (dataGridView1.Rows.Count > 0)
{
    if (dataGridView1.Rows[dataGridView1.CurrentRow.Index].IsNewRow != true)
    {
        dataGridView1.Rows.Remove(dataGridView1.CurrentRow);



    }