In that scenario first if you can design your classes like that
public class JobSeker
{
public string ID { get; set; }
public List<profile> ProfileCollection { get; set; }
}
public class Profile
{
public string ID { get; set; }
public bool isActive { get; set; }
}
</profile>
Now you can traverse the all the profiles based on the clicked profile and can alter the Active property.