You can use Simple AJAXControl for that. Try to Explore UpdatePanel and provide the UpdateProject Image for the same.
<asp:ScriptManager ID="ScriptManager1" runat="server" />
<asp:UpdateProgress runat="server" id="UpdateProgress">
<ProgressTemplate>
Loading Please Wait... // Here you can put a loading image as well
</ProgressTemplate>
</asp:UpdateProgress>
<asp:UpdatePanel runat="server" id="Panel">
<ContentTemplate>
Different ASP.NET Content that will participate in Partial Page rendering
<asp:Button runat="server" id="buttonSave" onclick="Save_Click" text="Save" />
</ContentTemplate>
</asp:UpdatePanel>
Hope this will help.