FileUpload Problem to SharePointList

 SPWeb web = SPContext.Current.Web;
            SPList list = web.Lists.TryGetList("Database");

           

                try
                {
                    if (list != null)
                    {
                        SPListItem item = list.Items.Add();

                        

                        item["Picture"] = FileUpload_Pic; // can i write like this for an fileupload, i am using it as an column on my sharepoint site
// i get this error, 
Column 'Picture' does not exist. It may have been deleted by another user.


                        

                        item.Update();