yes ...you can..
write a code what you want to execute on key press event..like
private void textBox1_KeyDown(object sender, KeyEventArgs ea)
if (e.KeyCode == Keys.Enter)
MessageBox.Show("Enwter Key Pressed ");
you can call that event where you want..here i'm called in button click..
private void button1_Click(object sender, EventArgs e)
i hope this may useful for you..