Yes. As Google would have shown you had you even tried to look.
A simple search using your subject line as the search term gave over 2 million hits, the first one being the full instructions from Microsoft!
Google[
^]
MSDN: How to: Upgrade to SQL Server 2008 R2[
^]
In future, please try to do at least basic research yourself, and not waste your time or ours.
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