See MSDN article DataView.RowFilter Property
To use it, you assign it a string that has something similar to the WHERE portion of an SQL statement. And you don't need to set the DataSource to the DataView object...you'd still set it to the DataTable object, but since the DataTable's DataView will have the filter, so will the grid...so you could do something like this:
DataGridView1.DataSource = DS.Tables(0)
DataGridView1.DataSource.DefaultView.RowFilter = "columnThatMightHaveBlanks<>''"