Sure you can invoke Excel trough a batch file but you would not be able to interact with the Excel instance. This sounds more like you want a regular application using a FileSystemWatcher and Excel interop. Or, you might be able to do this from a PowerShell script.
Why is common sense not common? Never argue with an idiot. They will drag you down to their level where they are an expert. Sometimes it takes a lot of work to be lazy Please stand in front of my pistol, smile and wait for the flash - JSOP 2012