I am not quite sure if this what you are really looking for but here are some links for you to take a look at:
Link 1[
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Link 2[
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Link 3[
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As far as I know in SQL Server 2000 you can import your excel sheet into a table in your database (via DTS) and then update your table from the excel table you might able to do that with 2008 as well. Look for into that as well.
Good luck,
OI