You can do like that
Step 1. Create a method that return full path src attribute of iframe
public string GetUrl(string id)
{
return "../../abc/xyz.aspx?Id =" + id;
}
Step 2. Define Ifranme and pass your id to generate url.
<iframe style=" width: 450px; height: 400px;" id="irm1" src='<%#GetUrl(Eval("Id").ToString()) %>' runat="server"></iframe>