Change your Arguments property string to something more readable:
startInfo.Arguments = string.Format("/a \"{0}\" /qb TARGETDIR=\"{1}.EXT\"", textBox1.Text, textBox1.Text);
Without knowing what you input, it's impossible to tell you what's really wrong. Are you providing a COMPLETE path to the target file or are you, foolishly, relying on relative path names?
The only other thing that may be wrong is why are you putting an extension on the path you pass to TARGETDIR?? Does the TARGETDIR directory structure exist before you try and execute this command?