You can use like this
<asp:DataGrid ID="DataGrid1" runat="server" Width="90%" AutoGenerateColumns="False"
ShowHeader="False">
<ItemStyle BackColor="DarkCyan"></ItemStyle>
<Columns>
<asp:TemplateColumn>
<ItemTemplate>
<a href="#"><%# Eval("gender")%></a>
</ItemTemplate>
</asp:TemplateColumn>
<asp:BoundColumn DataField="total" HeaderText="Total">
<ItemStyle HorizontalAlign="Center"></ItemStyle>
</asp:BoundColumn>
</Columns>
</asp:DataGrid>
And you can add Your Link.
You have to add a popup javascript file and chang the href value.
Examples :
Popup Examples[
^]
Thanks