Bind your dropdown like
SqlCommand command = new SqlCommand("select * from Employees",connection);
connection.Open();
SqlDataAdapter da=new SqlDataAdapter(command);
DataSet ds=new DataSet();
da.fill(ds);
DropDownList1.DataSource =ds;
DropDownList1.DataBind();
in
if(!Page.IsPostBack)
as well as
DropDownList1_SelectedIndexChanged
and define selected value of dropdown in definition itself. No need to make it in this code.
Regards.. :)