That's not really something that we can answer: once the image is loaded into the picture box the only size information available is the X and Y dimensions, as the actaul disk-based file size is not related directly to the image - it's a function of teh image content and the file type that it is saved in.
Many (nearly all) image file formats use compression so the size of the file will be different depending on the format you use: JPG files will be considerably smaller than the equivalent BMP file for example.
If you want to display the file size, you must read it when you load the image from the file and store it for later display. That's simple: the FileInfo class[^] will give you that, via the Length property.