It's pretty easy:
double d1 , d2, l1;
if (!double.TryParse(textbox1.Text, out d1)) throw new ArgumentException("Text box 1 needs to be numeric");
if (!double.TryParse(textbox2.Text, out d2)) throw new ArgumentException("Text box 2 needs to be numeric");
if (!double.TryParse(label1.Text, out l1)) throw new ArgumentException("Label 1 needs to be numeric");
label1.Text = (d1 + d2 + l1).ToString();