I'm reading your question to mean you want to use the WinUSB API to block a removable media device like a USB thumb drive or flash memory stick.
The short answer is you can't. The class of driver(s) for these types of devices is not WinUSB. Understand that WinUSB is two parts - a kernel driver and a user DLL. If the USB device does not use the WinUSB kernel driver, the user DLL can't help you talk to the device.
What you ask for is really a configuration issue more than a programming exercise.
Disable USB Storage In Windows 8 / 7 [How-To Guide] | Redmond Pie[
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