WinForms is just about as intuitive as it can get. Just drag Controls from your toolbox on to the designer surface.
Here[
^] are some guidelines that can help you create a user friendly Interface. Of course this is only one way to do it and it perhaps also depends on requirements (client wants to see lots of dialogs, client does not want to see dialogs, client wants everything shown in grids with 100 columns (yes, I've had such weird reqs...). Anyway, this should set you well on your way :)
Edit:
It might also help to sometimes open a standard Windows or Microsoft window/program and look at its UI. How are they aligned, what is the space between Controls etc. This will keep your UI conform to the overall Windows look.