how to we create the events in the VSTO 2010 c#

private void InternalStartup()
       {
           this.Startup += new System.EventHandler(ThisAddIn_Startup);
           this.Shutdown += new System.EventHandler(ThisAddIn_Shutdown);
           this.Application.DocumentOpen += new Word.ApplicationEvents4_DocumentOpenEventHandler(Application_DocumentOpen);
           this.Application.DocumentChange += new Word.ApplicationEvents4_DocumentChangeEventHandler(Application_DocumentChange);
           this.Application.DocumentBeforeClose += new Word.ApplicationEvents4_DocumentBeforeCloseEventHandler(Application_DocumentBeforeClose);
           this.Application.DocumentBeforeSave += Application_DocumentBeforeSave;
           ((Word.ApplicationEvents4_Event)Application).NewDocument += NewDocumentEvent;
       }