I got this solved myself. It was fun to test out to see if I was right or wrong. Or did I have to go into another way of doing it.
protected void TextBox3_TextChanged(object sender, EventArgs e)
{
int iTextBox2 = Convert.ToInt32(TextBox2.Text);
int iTextBox3 = Convert.ToInt32(TextBox3.Text);
if (iTextBox3 > iTextBox2)
{
int a = Convert.ToInt32(TextBox2.Text);
int b = Convert.ToInt32(TextBox3.Text);
TextBox4.Text = Convert.ToString(Math.Round((Math.Abs(b - a)) * 100.0 / ((a))));
}
else if (iTextBox3 < iTextBox2)
{
}