you can use requiredfieldvalidator and set the initial value as default value of the area drop down
check the sample codes given in the documentation
RequiredFieldValidator.InitialValue[
^]
by using requiredfieldvalidator you can check inputs without going to server side validation.
if you want to do the same in server side c# code; check the value of area code before you fetch the data from the database. if it is empty you can show message and exit the data loading method without executing database select statement