How do I do a insert into a database with a file upload without postback

protected void btn_Click(object sender, EventArgs e)
    {
        String name = TextBox1.Text;
        String desc = TextBox2.Text;

//CODE STOPS HERE, DOES NOT EXECUTE PASS THIS POINT
        String dir = Server.MapPath("files/News/" + FileUpload1.PostedFile.FileName);
        FileUpload1.PostedFile.SaveAs(dir);
        String SQL = String.Format(" INSERT INTO SF_news "
             + " (newsHeader, newsDescription, newsSrc, newsDate, newsYear) "
             + " VALUES "
             + " ('{0}', '{1}', '{2}', '{3}')",
             name, desc, FileUpload1.PostedFile.FileName);                                      
        new DBHelper().runSQL(SQL);
    }

<asp:ScriptManager ID="ScriptManager2" runat="server"></asp:ScriptManager>
 <asp:UpdatePanel ID="UpdatePanel1" runat="server">
   <ContentTemplate>
     <table>
       <tr id="hiddenForm" style="visibility:hidden;">
         <td colspan="4">
           <div>
<span>News Header: </span><span><asp:TextBox ID="TextBox1"runat="server"> </asp:TextBox></span>
<span>News Description: </span><span><asp:TextBox ID="TextBox2" runat="server"></asp:TextBox></span>
             <span>News File: </span><span>
<dx:ASPxUploadControl ID="FileUpload1"  runat="server" UploadMod="auto" Width="280px"></dx:ASPxUploadControl></span>
            <div>  
            <asp:Button ID="btn" runat="server" Text="Button" OnClick="btn_Click" />
    <input type="button" id="jsBtn" />
           </div>    
        </div>
       </td>
     </tr>
   </table> 
 </ContentTemplate>
</asp:UpdatePanel>