What is the best stack for web developement?

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Hi,

I want to know what are the differences and best ways of getting into full stack developement as a part timer. I work as full time .net backend and also frontend with basic js jquery.

I will try to pursue speed of developement cycle on those side projects. But if a project is big maybe a language or framework will be a better of a choice than another.

So for each i want to choose 2 methodologies or languages to get the job done.

I have searched online and found that react might be the best front end framework for me to use at the moment.

But for the backend i'm lost. Some use web api, some don't. Some use graphql, phoenix, rails, django. There is a lot on the backend and i just can't chose what to do with.

I would love to have an insight on the backend both for a one that gets job done fast and another for bigger applications.(both should be good with security)

Need to see if there are better things out there, instead of sticking only to c#.(keeping an open mind)

Thanks

What I have tried:

Researched online.
Used webapi mostly on c#.