An existing connection was forcibly closed by the remote host

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C#3.5

Below is a summary of the errors, details of these errors are listed later in the log.
* Activation of http:// //DOTNET.application resulted in exception. Following failure messages were detected:
+ Downloading http:/// /Application Files/DOTNET_1_0_0_2519/log4net.dll.deploy did not succeed.
+ Unable to read data from the transport connection: An existing connection was forcibly closed by the remote host.
+ An existing connection was forcibly closed by the remote host

What I have tried:

I have tried remove all bin file add newly and i checked sign also,but not sloved the issue.

please give any solution