Maybe your comboSelctIndChanged() fires for each added item when the comboBox is initialized.
You can set a Flag after
InitializeComponent();
However normally this should not occur, so search your code where the comboBox is being used and see what causes this strange behaviour.
If you can't find the problem, here is a dirty trick: you can delete the line from the form .Designer.cs
this.comboBox1.SelectedIndexChanged += new System.EventHandler(this.comboBox1_SelectedIndexChanged);
And put it in your code after you loaded all items.