Difference[
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Please check here, you will get to know. :)
.aspx is the viewpage
.aspx.cs is the class where the functionalities/events are defined
.aspx.designer.cs allows Visual Studio to give the user IntelliSense in the code-behind page for server controls created at design-time.
Like suppose we have a button on the view page i.e. .aspx and the click event is defined in the .aspx.cs.
Thanks
Hope this helps.
:)