Yes it is simple.
As you say you have pretty much figured out *everything* about DataSet, then Datatable row/column access would be easy for you.
As:
Dataset is a collection of tables (one or more).
C#:
myDataSet.Tables[0].Rows //0 for first table.
myDataSet.Tables[0].Columns //0 for first table
VB:
myDataSet.Tables(0).Rows
myDataSet.Tables(0).Columns
This should get you going.
Read all about the Dataset and tables in VB here:
The Tables of a Data Set[
^]