<asp:scriptmanager id="ScriptManager1" runat="server" xmlns:asp="#unknown">
</asp:scriptmanager>
<asp:updatepanel id="UpdatePanel1" runat="server" xmlns:asp="#unknown">
<contenttemplate>
<asp:timer id="Timer1" runat="server" interval="1000" ontick="Timer1_Tick">
</asp:timer>
<asp:gridview id="GridView1" runat="server" allowpaging="True" pagesize="20">
</asp:gridview>
<asp:label id="Label1" runat="server" text="Label"></asp:label>
</contenttemplate>
</asp:updatepanel>
Replace Gridview with Repeater control
and in code behind
protected void Timer1_Tick(object sender, EventArgs e)
{
BindGrid();
}