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If a sea-urchin can train an aquarium owner to become his hat manufacturer [^] by clever behavior, cannot we, the humble digi-serfs [^] powering the gig economy, learn to make program managers and corporate types our love-slaves ?
Can we not learn from the urchins' use of independently mobile spines that can collaborate to secure head-protection a paradigm for our collective mobilization ?
Think spiny !
«One day it will have to be officially admitted that what we have christened reality is an even greater illusion than the world of dreams.» Salvador Dali
You know collectively, in the same vein we could run absurd social experiments on program managers. Like getting the entire dev team to start speaking in Klingon, but only on Thursdays, and never bring it up or say anything about it. If they ask play dumb.
It might not be as practical as what the sea urchin does, but it could be entertaining.
You mean we have to speak English to PM's the rest of the week?
"I have no idea what I did, but I'm taking full credit for it." - ThisOldTony
"Common sense is so rare these days, it should be classified as a super power" - Random T-shirt
AntiTwitter: @DalekDave is now a follower!
(Talk about labor)
Fantastic planet urchin putting work in
Searching for pertinent verse minus the murderous diversion
Apologies won't lure me to the communal sob story
Nor will I sacrifice live style to benefit jury temperament
This old Green Goblin web cutter butts up against
Crayola daydream landscape spitting bedlam. Dead 'em
Charge the villagers nickels and nicotine to watch him fed to
One disgruntled kraken at high noon
We'll sell popcorn beer and balloons
I'm looking for scientific articles on some questions I have about how mRNA vaccines work.
First, I've read (and it seems to be basic biology) that mRNA does not alter the DNA in your cell nucleus. Anything that contradicts that?
But the questions I can't find answers to:
1. What cells does the mRNA vaccine "infect"?
2. Does your body see these cells as "hostile" now and kills them off?
3. How long do your cells produce the proteins that the mRNA encodes for? In other words, what is the basic biology of how long mRNA continues producing proteins?
This[^] was the article that first clued me in on how mRNA works. For me, this paragraph was the key.
From the article:
mRNA vaccines, in contrast, trick the body into producing some of the viral proteins itself. They work by using mRNA, or messenger RNA, which is the molecule that essentially puts DNA instructions into action. Inside a cell, mRNA is used as a template to build a protein. ‘An mRNA is basically like a pre-form of a protein and its (sequence encodes) what the protein is basically made of later on,’
That answer did it for me, although maybe I'm too easily satisfied.
The ribosomes in whichever cells the mRNA enters will assemble the protein for which it encodes (one that appears on the virus' outer surface, if I recall). This should train your immune system to attack that foreign protein, giving you protection against the virus. But the protection probably wears off eventually, at which time you'd need another mRNA injection.
Nature is a peer reviewed journal and is a go to source for me on stuff like this. I haven't looked for anything covid related - i already caught it anyway and am not into disaster pr0n so I try not to dwell on it but if i were to I'd start there.
They have lots of articles aside from the studies they publish and the articles can help you ask the right questions and know where to expand your hunt for info - that sort of thing.
This is the wikipedia entry in French:Mode d'action La production d'antigène dans le cytosol de la cellule conduit, après clivage par des protéases, à présenter les épitopes de l'antigène au complexe majeur d'histocompatibilité de classe I, qui active l'immunité cellulaire, et au complexe majeur d'histocompatibilité de classe II, qui active l'immunité humorale31. Every single word of this sentence requires hours to understand what it is about.
Finally, an additional point will merit investigation in the context of DC’s role in SARS-CoV-2 infection. In particular, the importance of the reported ability of estrogen to stimulate DC activity  needs explaining and clarifying as to why women appear less likely to die from Covid-19 than men.
It was only in wine that he laid down no limit for himself, but he did not allow himself to be confused by it.
― Confucian Analects: Rules of Confucius about his food
modified 24-Nov-20 10:12am.
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