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I just knocked my Keyboard (an old Dell) on the floor...the 'stuff' that came out! Stuff I don't eating! also some worrying pieces of 3D printing supports? If I ever cut myself on near it I will get a shot for tetanus...
Not the entire keyboard, though. Only the keys. I flip then all off and put them in one of these net bags made for holding pairs of socks together in your washing machine. While the dishwasher is cleaning them, I have easy access to the other surfaces of the keyboard, using a worn out toothbrush to clean the corners in the wells for keys.
The keys come out of the dishwasher perfectly clean and shining. Then they must be spread out in front of a fan for at least half a day to dry up the water that has come inside them. After that I must dig up an old keybard to get the keys back in place: I never look at the keys while typing, but if you ask me where, say, the 'l' key is located on the keyboard, I don't have clue. I just press the 'l' key, wherever it is located (This is similar to asking me to provide a list of which muscles I engage, in which order, to press that 'l' key: I can't. I just press the key.)
I guess I am less germaphobic than anyone I know. Amd I don't like peanut butter
Nevertheless, my fingers are not immune to loosing skin cells, to sweating, or whatever. I am often surprised by how much dust, sometimes rather fatty, is collected at the key sides that I do not touch while typing, and on the surfaces between the groups of keys. It must come from the air. Acutally, the keytops that my fingertip touches is more or less shiny, it is the sides that collect so much dirt that you can scrape it off.
That is the same both on my home PC and my office PC - and at the office, eating crackers with peanut butter while working is most certainly out of the question. Every half year or so, I take the office keyboard with me home to clean it the same way.
The same kind of deposits collects on the mouse, but its surfaces are easily accessible to be wiped with a cloth and some detergent.
And for the ambiguiety of the term "mouse"... In Norwegian, it is also a slang term for female private parts. You can imagine what we call the scroll wheel.
I've accidentally knocked a mouse off my desk, a joystick, pens and pencils, tipped over a cup of water (more than once)...but I have to think it takes a special kind of person to knock an entire keyboard off a desk and onto the floor. Was the whole system and monitor at risk of following?