WPF

<DataTemplate DataType="{x:Type local:MatrixElements}">
  <TextBlock Grid.Row="{Binding PositionY}" 
             Grid.Column="{Binding PositionX}"
             Text="{Binding Text}"
             ToolTip="{Binding ToolTip}" />
</DataTemplate>

<Window x:Class="TestMatrix.Window1"
    xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation"
    xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml"
    Title="Window1" Height="300" Width="300"
        xmlns:local="clr-namespace:TestMatrix"
        >

    <Window.Resources>
        <DataTemplate DataType="{x:Type local:MatrixElements}">
            <TextBlock Grid.Row="{Binding PositinX}"
                   Grid.Column="{Binding PositionY}"
                   Text="{Binding Text}"
                   ToolTip="{Binding ToolTip}"></TextBlock>
        </DataTemplate>
    </Window.Resources>
    <DockPanel>
        <UniformGrid x:Name="uGrid" Columns="64" Rows="64">          
        </UniformGrid>
    </DockPanel>
</Window>

<Window x:Class="Window1"
    xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation"
    xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml"
    xmlns:local="clr-namespace:WpfTrash"
    Title="Window1" Height="400" Width="600">
    <Window.Resources>
        <DataTemplate DataType="{x:Type local:MatrixElement}">
            <TextBlock Text="{Binding Text}" 
                       ToolTip="{Binding ToolTip}"
                       HorizontalAlignment="Center" />
        </DataTemplate>
    </Window.Resources>
    <ListBox Name="lstItems" Background="Green">
        <ListBox.ItemsPanel>
            <ItemsPanelTemplate>
                <Grid Name="grdTest"/>
            </ItemsPanelTemplate>
        </ListBox.ItemsPanel>
        <ListBox.ItemContainerStyle>
            <Style TargetType="{x:Type ListBoxItem}">
                <Setter Property="Grid.Row" 
                        Value="{Binding Content.PositionX, 
                                        RelativeSource={RelativeSource Self}}" />
                <Setter Property="Grid.Column" 
                        Value="{Binding Content.PositionY, 
                                        RelativeSource={RelativeSource Self}}" />
            </Style>
        </ListBox.ItemContainerStyle>
    </ListBox>
</Window>

Class Window1 

    Private Sub Window1_Loaded(ByVal sender As Object, _
                               ByVal e As System.Windows.RoutedEventArgs) _
                               Handles Me.Loaded
        'create some dummy elements and set the items source of the listbox
        Dim elems As New List(Of MatrixElement)
        Dim curElem As MatrixElement
        For r As Integer = 0 To 63
            curElem = New MatrixElement
            curElem.PositionX = r
            curElem.PositionY = r
            curElem.Text = String.Format("{0}, {0}", r)
            elems.Add(curElem)
        Next
        lstItems.ItemsSource = elems

        'finds the actual grid used by the list box
        Dim d As DependencyObject
        d = VisualTreeHelper.GetParent( _
                lstItems.ItemContainerGenerator.ContainerFromIndex(0))
        While Not (d Is Nothing OrElse d.GetType() Is GetType(Grid))
            d = VisualTreeHelper.GetParent(d)
        End While
        If d Is Nothing Then Exit Sub

        'once you have the grid, you need to add the rows and columns
        Dim rd As RowDefinition
        Dim cd As ColumnDefinition
        Dim grd As Grid = CType(d, Grid)
        lstItems.SetValue(Grid.IsSharedSizeScopeProperty, True)
        For i As Integer = 0 To 63
            rd = New RowDefinition
            rd.Height = New GridLength(1, GridUnitType.Star)
            rd.SharedSizeGroup = "MatrixElemRowGroup"
            grd.RowDefinitions.Add(rd)
            cd = New ColumnDefinition
            cd.Width = New GridLength(1, GridUnitType.Star)
            cd.SharedSizeGroup = "MatrixElemColumnGroup"
            grd.ColumnDefinitions.Add(cd)
        Next
        'this is just for debugging purposes
        grd.ShowGridLines = True
    End Sub

End Class

Dim d As DependencyObject        
d = VisualTreeHelper.GetParent( _                
lstItems.ItemContainerGenerator.ContainerFromIndex(0))

static class HelpUtility
{
  static HelpUtility()
  {
    CommandManager.RegisterClassCommandBinding(typeof(FrameworkElement),
      new CommandBinding(ApplicationCommands.Help,
            new ExecutedRoutedEventHandler(Executed),
            new CanExecuteRoutedEventHandler(CanExecute))
        );
  }
  public static string GetHelpKey(DependencyObject dObj)
  {
    return dObj.GetValue(HelpKeyProperty).ToString();
  }
  public static void SetHelpKey(DependencyObject dObj, string value)
  {
    dObj.SetValue(HelpKeyProperty, value);
  }
  public static readonly DependencyProperty HelpKeyProperty =
     DependencyProperty.RegisterAttached("HelpKey", 
     typeof(string), typeof(HelpUtility));

  private static void CanExecute(object sender, CanExecuteRoutedEventArgs e)
  {
    FrameworkElement fe = sender as FrameworkElement;
    if (fe != null)
    {
      if (HelpUtility.GetHelpKey(fe) != null)
        e.CanExecute = true;
    }
  }
  private static void Executed(object sender, ExecutedRoutedEventArgs e)
  {
    System.Windows.Forms.Help.ShowHelp(null, @"HelpFile.chm", 
      System.Windows.Forms.Help.HelpNavigator.Index); // Show the index...
  }
}

<... standard window definitions here, but the next bit is the charm
  xmlns:help="clr-namespace:...mynamespace...">
<Grid>
  <Grid.ColumnDefinitions>
    <ColumnDefinition Width="auto" />
    <ColumnDefinition Width="*" />
  </Grid.ColumnDefinitions>
  <Grid.RowDefintions>
    <RowDefinition />
  </Grid.RowDefintions>
    <TextBox Grid.Column="0" Grid.Row="0" Name="NameField" help:HelpKey="MyName" />
</Grid>
</Window>