HI use this
And you can use the following link
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Dim rows As IEnumerable(Of DataRow) = DataTableObject.Rows.Cast(Of DataRow)().Where(Function(r) r("EmployeeId").ToString() = 123 AndAlso r("Name").ToString() = Abdul)
rows.ToList().ForEach(Function(r) r.SetField(EmployeWorking, Y))
rows.ToList().ForEach(Function(r) r.SetField(EmployeeLocation, Microsoft))