How to delete columns of multiple tables with one query

That doesn't delete columns, that deletes rows.

Columns -->   ID    Name          Address
Rows v
                  1    Joe Smith     2 Bread Street
                  2    Mike Hunt     42, Ballard way
                 ...

Delete a column, and it removes all the data in that column for all rows, you don't get a WHERE clause with that!

And don't do anything like you show in your query! Never concatenate strings to build a SQL command. It leaves you wide open to accidental or deliberate SQL Injection attack which can destroy your entire database. Always use Parameterized queries instead.

When you concatenate strings, you cause problems because SQL receives commands like:

SELECT * FROM MyTable WHERE StreetAddress = 'Baker's Wood'

The quote the user added terminates the string as far as SQL is concerned and you get problems. But it could be worse. If I come along and type this instead: "x';DROP TABLE MyTable;--" Then SQL receives a very different command:

SELECT * FROM MyTable WHERE StreetAddress = 'x';DROP TABLE MyTable;--'

Which SQL sees as three separate commands:

SELECT * FROM MyTable WHERE StreetAddress = 'x';

A perfectly valid SELECT

DROP TABLE MyTable;

A perfectly valid "delete the table" command

--'

And everything else is a comment.
So it does: selects any matching rows, deletes the table from the DB, and ignores anything else.

So ALWAYS use parameterized queries! Or be prepared to restore your DB from backup frequently. You do take backups regularly, don't you?

Fix that through your whole app, and then think about how the table data you want to delete is organised and related: we can't help you at the moment because we have no idea how your DB is laid out.