please Correct this replace code

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C#

Windows

application

Hi developers
I am writing a replace method for a dataset to replace wildcards or regular expression from a csv file which is loaded in dataset .

foreach (DataRow datarow in dataset.Tables[0].Rows)
{
  foreach (DataColumn datacol in dataset.Tables[0].Columns)
  {
    datarow[datacol] = Regex.Replace(datarow[datacol].ToString(), comma.ToString(), slash.ToString());
    datarow[datacol] = Regex.Replace(datarow[datacol].ToString(), colon.ToString(), Blank.ToString());
  }
}

This method is working good but after replacing wildcards or a regular Expression an error is thrown.
"Input string was not in a Correct format ,Could not Store ??? in PRIORITY Column. Expected type Int32"
Please solve the problem that is raised in the code.