Mobile Device With Barcode Reader as Simple inpout in a desktop Pc

In order to access the hardware you'll need system API's and documentation on how to call functions. So start with downloading an sdk (software development kit) and documentation and try some example applications.

I've used a regular laser-scanner for barcodes and they work essentially like a keyboard. So if you are trying to bind on KeyPress or KeyDown events you'll wind up with a big headache since it will only register the FIRST character and ignore the others. I had to add a timer to check if there was input in the textbox before processing. Ruard is correct you'll want to get ahold of the SDK and see what sort or output you can gather from the phone itself. Also, developing an application ON THE PHONE that uses the scanner for input and then re-sends the data via web-services to your main app could be a viable solution depending on your needs.