You don't listen much, do you? As stated in your other copy of this same question, for a Xamarin app, you should NOT be connecting directly to a database engine. You SHOULD be calling a web service that sits in front of your SQL Server where the web service is doing the database work for you and returning results back to the client. Your Xamarin app should be calling the web service, not the database.
Your other copy of the question:
Connection string to MS SQL database android/iOS app[
^]
Next, a little pet peeve of mine. You do not have to specify the port number in the connection string unless your server is not using the standard port number, 1433.