error to run web application in iis8 in windows application

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C#

C#4.0

Hello friends
I cannot able to run web application in iis8. it show access denied.401.3 You do not have permission to view this directory or page using the credentials you supplied (access denied due to Access Control Lists). Ask the Web server's administrator to give you access to 'C:\Users\ramanan\Documents\Visual Studio 2010\Projects\trainingsite'.but acutally i gave the permission to iis_iusrs. and i have changed in the applicationhost.webconfig for handler and module to allow.but still my trainingsite does not run. i am using windows8.