I think you can give the property in design page itself.
<asp:DropDownList ID="DropDownListname" runat="server">
<asp:ListItem Value="0">first value</asp:ListItem>
<asp:ListItem Value="2">second value</asp:ListItem>
<asp:ListItem Value="3">third value</asp:ListItem>
</asp:DropDownList>
Or try
dropdownlist.selecteditem='That String'