If the actual folder names are unknown you may do split and join to achieve this (with a bit of LINQ)...
string src = "C:\\Folder1\\Folder2\\Folder3\\Folder4";
string[ ] arr = src.Split( new char[ ] { '\\' } );
arr = arr.Where( ( value, index ) => index > 2 ).ToArray( );
string rv = string.Join( "\\", arr );