String FileName = "FileName.txt";
String FilePath = "C:/....";
System.Web.HttpResponse response = System.Web.HttpContext.Current.Response;
response.ClearContent();
response.Clear();
response.ContentType = "text/plain";
response.AddHeader("Content-Disposition", "attachment; filename=" + FileName + ";");
response.TransmitFile(FilePath);
response.Flush();
response.End();