Very har to answer seing that you don't give us any specific information. It depends on how the text is displayed and/or entered.
If you show the text in a TextBox and let the user change it there, it's simple.
Save the original text in a string variable and compare the string variable to the textbox' text before saving
If Textbox1.Text <> theValueToBeginWith Then
'Save the text
Else
'Don't bother
End If