Put control inside update panel which you want to update.
Inside trriger tag of Update Panel specify eventname and controlname of control(Image Button)
<%@ Page Language="C#" AutoEventWireup="true" CodeFile="Default.aspx.cs" Inherits="_Default" %>
<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN"
"http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
<html xmlns="http://www.w3.org/1999/xhtml" >
<head runat="server">
<title>Untitled Page</title>
</head>
<body>
<form id="form1" runat="server">
<asp:ScriptManager EnablePartialRendering="true"
ID="ScriptManager1" runat="server"></asp:ScriptManager>
<div>
<asp:UpdatePanel ID="UpdatePanel1" runat="server"
UpdateMode="Conditional">
<ContentTemplate>
<asp:Label ID="Label1" runat="server" /><br />
<asp:Button ID="Button1" runat="server"
Text="Update Both Panels" OnClick="Button1_Click" />
<asp:Button ID="Button2" runat="server"
Text="Update This Panel" OnClick="Button2_Click" />
</ContentTemplate>
</asp:UpdatePanel>
<asp:UpdatePanel ID="UpdatePanel2" runat="server"
UpdateMode="Conditional">
<ContentTemplate>
<asp:Label ID="Label2" runat="server" ForeColor="red" />
</ContentTemplate>
<Triggers>
<asp:AsyncPostBackTrigger ControlID="Button1" EventName="Click" />
</Triggers>
</asp:UpdatePanel>
</div>
</form>
</body>
</html>