You need to hold all holidays date in a array format.
then you can use
beforeShowDay
event :
eg :
var array = ["2015-12-30", "2015-12-26", "2015-12-23"]
$(document).ready(function () {
$('#txtCalander').datepicker({
beforeShowDay: function (date) {
var string = jQuery.datepicker.formatDate('yy-mm-dd', date);
return [array.indexOf(string) == -1]
}
});
});
Good luck